New pre-print: Distinguishing Protein and Gene Delivery Enables Characterization and Bioengineering of Extracellular Vesicle-Adeno-Associated Virus Vectors

We’re excited to share our new pre-print which develops an assay which distinguishes protein vs. gene delivery to examine effects of surface-modification on extracellular vesicle encapsulated adeno-associated virus (EV-AAV)-mediated gene delivery. Congrats to Jonathan Boucher and the whole EV-AAV team! Check out the pre-print here!

New paper: Exploring Structure—Function Relationships in Engineered Receptor Performance Using Computational Structure Prediction

We’re excited to share our recent work examining how protein structure prediction tools can be used to explore structure-function relationships in synthetic receptors. Our work was featured on the cover of GEN Biotechnology Vol. 4, No. 1. Congratulations to Dr. Will Corcoran, Amparo Cosio, and our alumni Dr. Hailey Edelstein. Check out the paper here!

New paper: Developing, characterizing, and modeling CRISPR-based point-of-use pathogen diagnostics

We’re excited to share our recent work developing a nucleic acid sequence-based amplification pathogen diagnostic for SARS-CoV-2, with 20-200 aM sensitivity. We also develop an explanatory model to gain mechanistic insight into reaction performance. Congratulations to Dr. Katie Dreyer, Dr. Kate Dray, and our wonderful collaborators in the Lucks, Jewett, and Mangan groups. Check out the paper here!

New preprint: Developing, characterizing and modeling CRISPR-based point-of-use pathogen diagnostics

We’re excited to share our recent work developing a nucleic acid sequence-based amplification pathogen diagnostic for SARS-CoV-2, with 20-200 aM sensitivity. We also develop an explanatory model to gain mechanistic insight into reaction performance. Congratulations to Katie, Dr. Kate Dray, and our wonderful collaborators in the Lucks, Jewett, and Mangan groups. Check out the preprint here!